A war has been raging between the Vampires and Lycan for centuries, Selene (Beckinsale) is a death dealer, assigned to hunt down and eradicate the last of the Lycan. When she comes across Michael Corvin (Speedman) who holds the key to end the war she must decide where her allegiances will lie.
After returning from a wedding reception, a couple staying in an isolated vacation house receive a knock on the door in the mid-hours of the night. What ensues is a violent invasion by three strangers, their faces hidden behind masks. The couple find themselves in a violent struggle, in which they go beyond what either of them thought capable in order to survive.
Underworld: Evolution continues the saga of war between the vampires and the Lycans. The film goes back to the beginnings of the ancient feud between the two tribes as Selene, the beautiful vampire heroine, and Michael, the lycan hybrid, try to unlock the secrets of their bloodlines. This will be a modern tale of action, intrigue and forbidden love, which takes them into the battle to end all wars as the immortals must finally face their retribution.